Francis will make the trip at the request of the Turkish president, Recep Tayyip Erdoğan, Ecumenical Patriarch Bartholomew I and the Turkish bishops.
The Middle East, especially Iraq and Syria, are experiencing "terrorism of previously unimaginable proportions" in which the perpetrators seem to have absolutely no regard for the value of human life, Pope Francis said.
"It seems that the awareness of the value of human life has been lost; it seems that the person does not count and can be sacrificed to other interests. And all of this, unfortunately, with the indifference of many," he said during a special meeting at the Vatican on the Middle East.
Pope Francis praised Blessed Paul VI as a "humble and prophetic witness of love for Christ and his church" at Paul's beatification Mass on Sunday.
Analysis: The synod was a victory for openness and discussion in the church, and the final document is an invitation for everyone to join that discussion.
As the Synod of Bishops on the family's final report narrowed its tone of openness, Pope Francis called on bishops Saturday to find a path between doctrine and reality.
Following is Vatican Radio's provisional translation of Pope Francis' address to the Synod Fathers:
Dear Eminences, Beatitudes, Excellencies, Brothers and Sisters,
With a heart full of appreciation and gratitude I want to thank, along with you, the Lord who has accompanied and guided us in the past days, with the light of the Holy Spirit.
In a message to families, the Synod of Bishops outlines a situation of "light and shadow" around the world and says married love "shines out brightly, warming bodies and souls."
Pope Paul VI was best known for reaffirming the church's ban on artificial contraception, but Pope Francis is focusing on Paul's other groundbreaking, though often overlooked, contributions.
Q and A: Archbishop Joseph Kurtz says the synod on the family is starting a process of discernment among the church's prelates.
"Saying that the doctrine will never change is a restrictive view of things. ... The core of the Catholic church remains the Gospel, but have we discovered everything?"